Creating Health Access for Next Generation Equity (CHANGE)

For its 2026 funding cycle, the AstraZeneca Foundation held an open call for applications from April 1, 2026 through May 5, 2026 at 5:00 p.m. E.T. The 2026 open application period is now closed.

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The AstraZeneca Foundation’s CHANGE program accepts applications from US-based nonprofit organizations with a 501(c)(3) designation, public schools, government entities and municipal organizations that are allowed to accept tax deductible, charitable contributions. Additional exclusions apply.

In 2026, nonprofit organizations applying for a CHANGE grant must meet the following criteria:

• Organizations must serve communities in one of the following locations in which AstraZeneca has a footprint: California, Delaware, Maryland, Massachusetts or Texas.
• Organizations must have a total revenue of $12 million or less in their most recent tax year.
• Organizations must work to improve access to quality healthcare for populations experiencing health disparities.
• Organizations must provide services tailored to the needs of their communities to help improve healthcare access while considering social drivers of health that impact community members. This may include but is not limited to:

        • Providing access to healthcare services (e.g., screenings, wellness and prevention services);

        • Coordinating healthcare services (e.g., via case managers, health coaches); and

        • Mitigating barriers that impact access to healthcare services (e.g., transportation, affordability, physical accessibility, language).

• Greater weight is given to organizations that provide services in areas of low-income and/or remote/rural areas and include a focus on screenings, early detection, treatment and/or continuity of care for cardiovascular, renal, respiratory or immunologic diseases and/or cancers.
• Additional preference will be given to organizations establishing new partnerships and broader coalitions of community-based organizations or expanding existing partnerships with the intent of breaking down institutional silos and facilitating access to quality healthcare through inter-institutional collaboration.

Review the detailed criteria here.

The AstraZeneca Foundation accepted applications from eligible US-based nonprofit organizations from April 1, 2026 through May 5, 2026 at 5:00 p.m. E.T. The 2026 open call for applications has closed.

Organizations selected as finalists will be notified and invited to submit a full, formal application through the CyberGrants platform beginning June 10, 2026 through July 8, 2026 at 5:00 p.m. E.T. A selection of finalists will receive grants based on funding availability and decision by the Foundation’s Board of Trustees.
 

Application Process and Key Dates:

*Organizations selected for funding will need to review and sign a Letter of Agreement prior to receiving funds. Grant activities may begin upon receipt of grant funds.

• 2025 CHANGE Grant Awardees
• 2024 CHANGE Grant Awardees
• 2023 CHANGE Grant Awardees
• 2023 Community Health Grant Awardees

*In 2023, final grants were awarded to current Connections for Cardiovascular Health^SM Next Generation grant awardees for their efforts to improve community health.