Topher Brooke


William oversees US business development activities to fuel AstraZeneca’s pipeline and leverage transformational commercial capabilities.

Prior experience

Prior to his current role, William held a range of positions of increasing responsibility in AstraZeneca’s commercial, business development and legal organizations. Of particular note, he managed a multi-billion dollar portfolio of primary care brands. Previously, he led AstraZeneca’s Healthcare Innovation Center, which focused on pharmaceutical adjacencies such as devices, diagnostics and other healthcare technologies.

During his career William has managed the creation of a broad spectrum of Healthcare alliances both within and beyond traditional Pharma/biotech.


  • Bachelor of science, chemical engineering from University of Delaware
  • Law degree, juris doctorate from Villanova University School of Law