CRESTOR celebrates 10th anniversary – AstraZeneca announced FDA approval of CRESTOR on August 13, 2003
By Dr Philip de Vane, Executive Director of Medical Affairs and Strategic Development at AstraZeneca
As we mark the 10-year anniversary of the US approval of CRESTOR® (rosuvastatin calcium), AstraZeneca has a great deal of pride in celebrating this important milestone knowing the impact the brand has made in the treatment of high cholesterol and slowing the progression of atherosclerosis (the buildup of plaque in arteries).
AstraZeneca announced the US Food and Drug Administration approval of CRESTOR on August 13, 2003. Since then, CRESTOR has received regulatory approval in more than 100 countries worldwide. CRESTOR is backed by clinical research that spans 13 years, including over 120 ongoing or completed clinical trials and includes more than 67,000 patients worldwide.
Over the past decade, AstraZeneca has worked to develop patient education programs to help educate Americans about cholesterol management and atherosclerosis. However, we recognize there is still more work to be done, sincean estimated 31.9 million US adults have high cholesterol, according to the 2013 update to the American Heart Association’s Heart Disease and Stroke Statistics.
With this in mind, we remain committed to helping increase awareness of high cholesterol and other risk factors that can contribute to the progression of atherosclerosis among adults, particularly those at increased risk.
We’re confident that CRESTOR will remain an important treatment option for appropriate patients for years to come.
When diet and exercise alone aren’t enough to lower cholesterol, adding CRESTOR can help. In adults, CRESTOR is prescribed along with diet to lower high cholesterol and slow the buildup of plaque in arteries as part of a treatment plan to lower cholesterol to goal.
CRESTOR is not right for everyone. Do not take CRESTOR if you are nursing, pregnant or may become pregnant; have liver problems; or have had an allergic reaction to CRESTOR. Your doctor should do blood tests to check your liver before starting treatment and if you have symptoms of liver problems while taking CRESTOR. Call your doctor right away if you have unexplained muscle pain or weakness, especially with fever; have muscle problems that do not go away even after your doctor told you to stop taking CRESTOR; feel unusually tired; or have loss of appetite, upper belly pain, dark urine, or yellowing of skin or eyes. These could be signs of rare but serious side effects. Elevated blood sugar levels have been reported with statins, including CRESTOR. The most common side effects may include headache, muscle aches, abdominal pain, weakness, and nausea. Memory loss and confusion have also been reported with statins, including CRESTOR. Tell your doctor and pharmacist about other medicines you are taking. See www.CRESTOR.com
Please see full Prescribing Information.